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Transdermal Ectopic Decalcification Platform
PCT Patent Pending (WIPO) WO 2026/187244 | Official WIPO Patent Published
Next-Generation Transdermal Technology for Ectopic Calcium Dissolution
Next-Generation Transdermal Technology for Ectopic Calcium Dissolution
A bio-compatible, high-velocity permeation platform engineered for non-invasive clearance of pathological calcification in vascular and musculoskeletal tissues. Description of an effort and why it matters
Key Technological Highlights
Ultra-Fast Transdermal Kinetics: Human in vivo GC-MS data demonstrate a 37.5% increase in systemic active citrate within 10 minutes post-application without physical enhancement devices.
Targeted Decalcification: Serial 5-month radiological evaluation shows structural fragmentation and clearance of arterial and tendinous calcific burdens (with vascular applications under ongoing investigation).
Tissue-Selective Safety: Selectively targets labile, pathological ectopic calcium while fully preserving structural bone architecture.
Self-Regulating Homeostatic Plateau: Demonstrates state-dependent vascular stabilization, preventing uncontrolled physiological escalation.
Therapeutic Applications
Field
Primary Indication
Cardiovascular Medicine
Arterial stiffness reduction, vascular elasticity restoration, Mönckeberg's arteriosclerosis management.
Sports Medicine & Rheumatology
Non-invasive treatment of calcific tendinopathies, enthesopathies, and chronic calcaneal spurs.
Intellectual Property & Commercial Opportunity
IP Status: International Patent Application filed under the PCT framework at WIPO (OSIM, March 2025).
Opportunity: DECALCIFIL is available for worldwide exclusive licensing, co-development, or asset acquisition. Complete clinical datasets, GC-MS chromatography profiles, and radiological files are available upon execution of a standard Non-Disclosure Agreement (NDA).
Questions?
Questions?
Inquiries & Business Development:
Filo Muresan — Founder & Principal Inventor
✉️ filo@decalcifil.com
© 2026 DECALCIFIL . All Rights Reserved.
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